i2b2 aspires to overcome two major obstacles to translating the discoveries of the genomic era into safer, more effective and more personalized healthcare. The first obstacle is comprised of the computational challenges of discovery across large, heterogeneous data
sets routinely obtained in clinical care and the genome-wide measurements made of the corresponding patients. The second obstacle is the lack of knowledge of genomic-level physiology and how to study it.
The goal of i2b2 therefore is to develop the science and the engineering required to enable the clinical investigators of academic medical centers to conduct clinical research that is informed by state-of-the-art genomics and biomedical informatics.